Week 15 Thursday Night Football presents an exciting NFC West divisional matchup with significant postseason implications as the San Francisco 49ers (6-7) take on the Los Angeles Rams (7-6). Despite injuries to critical players like Christian McCaffrey (knee), Jordan Mason (ankle), and Brandon Aiyuk (knee), the 49ers remain a competitive offensive unit, ranking 11th in the league with 22.7 points per game. Coming off a dominant 38-point performance against the Bears, they’ll rely on players like Brock Purdy, George Kittle, Jauan Jennings, and Deebo Samuel Jr. to secure a crucial win.
DFS enthusiasts will want to consider Brock Purdy for their lineups. Drafted last in 2022, Purdy has established himself as a reliable quarterback, ranking 12th in the league with 3,032 passing yards and averaging 252.7 yards per game. His previous matchup against the Rams saw him rack up 292 yards and three touchdowns. The Rams’ defense, which ranks 23rd in passing yards allowed per game and struggles against the pass (8.0 yards per attempt), is vulnerable, making Purdy a top DFS option.
On the other side, Rams running back Kyren Williams is another standout DFS choice. Williams leads all NFL running backs in snap counts, playing 86% of offensive snaps this season, showcasing his importance in the Rams’ offensive strategy. With 87 rushing yards and two touchdowns against the Bills last week, he’s proven to be a consistent and productive option. The 49ers’ defense, which has slipped to 21st in scoring (23.7 points per game allowed), has struggled to contain opposing RB1s recently, giving Williams another opportunity to shine.
DFS expert Mike McClure, with over $2 million in career winnings, highlights these players as key picks for Thursday’s game. McClure’s proprietary prediction model evaluates matchups, trends, and injuries, offering valuable insights for maximizing DFS lineups. For further analysis and additional undervalued picks, fans can visit SportsLine for McClure’s full breakdown.
Whether stacking Purdy with Kittle or banking on Williams’ all-around contributions, this game offers plenty of DFS value in a matchup critical for both teams’ playoff aspirations.
